A Research Upon the Action of Alcohol Upon the Circulation

1905 DETAILED PHYSIOLOGIC STUDY OF THE EFFECTS OF ALCOHOL ON CARDIOVASCULAR FUNCTION BY PROMINENT PHARMACOLOGIST AT UNIVERSITY OF PENNSYLVANIA. 11 1/2 inches tall offprint, original gray printed paper covers, contemporary ink inscription of title and unintelligible signature dated Nov 6/05 on cover. 3 plates, edges worn, text unmarked and very good. The paper is notable in that in the Introduction, the contribution of each author is clearly stated, as is the case in the 21st century: It is perhaps proper to state that although the actual work of making the experiments was chiefly performed by Doctor Hoyt, Doctor Wood took part in and overlooked all experiments of importance, so that the authors of this memoir are equally responsible for the accuracy of the experimental work and of its results. The authors conclude that the experiments performed in dogs reveal that the primary circulatory effect of alcohol is cardiac stimulation and vasodilation due to vasomotor suppression. They allow themselves to speculate in the last paragraph that in the human, cerebral vasodilation is also a likely effect: any habitue of feasts where alcoholic drinks circulate freely knows full well the increase of amount and brilliancy of conversation which occurs pari passu with the flushing of the cheeks. Evidently it is probable that this cerebral excitsment and increased activity due not to the direct action of the drug upon the brain but to the enormously increased flow of blood running riot through the cerebrum. HORATIO C. WOOD (1841 - 1920) started studying medicine at the University of Pennsylvania in 1859, and graduated in 1862. While still a student, Wood wrote his first scientific paper, reporting on the Carboniferous flora of the United States. He acted as a surgeon for the Northern army during the American Civil War, including a spell at the front-line Fairfax Seminary General Hospital. After the War, Wood supplemented his income by teaching privately at the medical school. He was awarded the chair of botany at the University, and was elected Clinical Lecturer in Nervous Diseases at the medical school in 1873, later rising to Clinical Professor. He was made Professor of Materia Medica and Pharmacy in 1876, and added General Therapeutics to his title later that year. Wood's fame was established by his 1874 work Treatise on Therapeutics, which became the principal textbook in materia medica and therapeutics for 30 years.

Product Info

Publisher: Memoirs of the National Academy of Sciences

Year: 1905

Type: Used

Binding: Softcover

First Edition

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